Absence of the ROS Scavenger DJ-1 Paradoxically Protects Mice from Obesity and Insulin Resistance
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چکیده
منابع مشابه
Deficiency of Phosphoinositide 3-Kinase Enhancer Protects Mice From Diet-Induced Obesity and Insulin Resistance
OBJECTIVE Phosphoinositide 3-kinase enhancer A (PIKE-A) is a proto-oncogene that promotes tumor growth and transformation by enhancing Akt activity. However, the physiological functions of PIKE-A in peripheral tissues are unknown. Here, we describe the effect of PIKE deletion in mice and explore the role of PIKE-A in obesity development. RESEARCH DESIGN AND METHODS Whole-body PIKE knockout mi...
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ژورنال
عنوان ژورنال: Canadian Journal of Diabetes
سال: 2013
ISSN: 1499-2671
DOI: 10.1016/j.jcjd.2013.08.199